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Article

Discriminating Heterogeneous Trajectories of Resilience and Depression After Major Life Stressors Using Polygenic Scores.

JAMA psychiatry - 1 Jul 2021

Schultebraucks Katharina, Choi Karmel W, Galatzer-Levy Isaac R, Bonanno George A

Abstract excerpt

Importance: Major life stressors, such as loss and trauma, increase the risk of depression. It is known that individuals show heterogeneous trajectories of depressive symptoms following major life stressors, including chronic depression, recovery, and resilience. Although common genetic variation has been associated with depression risk, genomic factors that could help discriminate trajectories of risk vs...

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Identifiers

PMID: 33787853
DOI: 10.1001/jamapsychiatry.2021.0228
PMCID: PMC8014197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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