Article

Psychological resources confer greatest protection against late-life depression in genetically vulnerable adults

2026-06-17

Abstract excerpt

<title>Abstract</title> <p>How life-course experiences shape depression in later life remains one of the central questions in human aging. We analyzed approximately 35 years of sociogenomic longitudinal data from 9,005 European-ancestry individuals in the Wisconsin Longitudinal Study. Machine learning models were applied to 426 variables measured at mean ages 35.6, 53.0, and 64.2 to predict depressive symptoms at...

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Literature Corpus work: 37b3aea5-3f4b-5964-8455-5ca05bf61f2c
DOI: 10.21203/rs.3.rs-9990161/v1

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