Article
Genetic heterogeneity in depressive symptoms following the death of a spouse: Polygenic score analysis of the US Health and Retirement Study
2016-07-26
Abstract excerpt
Experience of stressful life events is associated with risk of depression. Yet many exposed individuals do not become depressed. A controversial hypothesis is that genetic factors influence vulnerability to depression following stress. This hypothesis is most commonly tested with a “diathesis-stress” model, in which genes confer excess vulnerability. We tested an alternative model, in which genes may buffer agains...
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Identifiers and source
- Literature Corpus work
- 4e738664-b3b1-5229-add5-d8bff4654c63
- DOI
- 10.1101/065847