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Article

Differences in anatomoclinical profiles between RAS-Mutated and Wild-Type colorectal cancers in an Eastern Algerian Cohort.

African health sciences - 1 Mar 2026

Massinissa Yahia, Benhouda Afaf, Khadraoui Hachani, Benouda Djahida, Khettache Wafa, Soussi Atika

Abstract excerpt

Background: Colorectal cancer (CRC) ranks as the third most prevalent malignancy globally, with incidence rates rising steadily in Algeria. Prognostic assessment of CRC increasingly relies on molecular profiling, particularly mutations in the KRAS gene a critical determinant of resistance to anti-EGFR therapies in metastatic disease. Objectives: This study investigates the KRAS mutational spectrum and its...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42063916
DOI: 10.4314/ahs.v26i1.12
PMCID: PMC13126134

Genes

KRAS
EGFR

Variants

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