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Article

Phenome-Wide Investigation of the Causal Associations Between Pre-Pregnancy Obesity Traits and Gestational Diabetes: A Two-Sample Mendelian Randomization Analyses.

Reproductive sciences (Thousand Oaks, Calif.) - 1 Feb 2025

Hu Mengjin, Li Xiaosong, Wu Jiangong, Li Boyu, Xia Jinggang, Yang Yuejin, Yin Chunlin

Abstract excerpt

Pre-pregnancy obesity was associated with gestational diabetes in observational studies, but whether this relationship is causal remains to be determined. To evaluate whether pre-pregnancy obesity traits causally affect gestational diabetes risk, a two-sample Mendelian randomization (MR) analysis was performed utilizing summary-level statistics from published genome-wide association studies (GWAS)....

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Identifiers

PMID: 38789873
DOI: 10.1007/s43032-024-01577-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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