Article
Causal association of childhood obesity with cancer risk in adulthood: A Mendelian randomization study.
International journal of cancer - 1 Oct 2021
Fang Xuexian, Wang Xinhui, Song Zijun, Han Dan, Yin Xiangju, Liu Bingqing, Chen Luyi, Zhang Ronghua, Lian Fuzhi, Sui Xinbing
Abstract excerpt
In observational studies of children and adolescents, higher body weight has been associated with distinct disease outcomes, including cancer, in adulthood. Therefore, we performed a two-sample Mendelian randomization (MR) study to evaluate the causal effect of childhood obesity on long-term cancer risk. Single-nucleotide polymorphisms associated with higher childhood body mass index (BMI) from large-scale...
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