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Article

Integrating disease and drug-related phenotypes for improved identification of pharmacogenomic variants.

Pharmacogenomics - 1 Apr 2021

Ouellette Tom W, Wright Galen Eb, Drögemöller Britt I, Ross Colin Jd, Carleton Bruce C

Abstract excerpt

Aim: To improve the identification and interpretation of pharmacogenetic variants through the integration of disease and drug-related traits. Materials & methods: We hypothesized that integrating genome-wide disease and pharmacogenomic data may drive new insights into drug toxicity and response by identifying shared genetic architecture. Pleiotropic variants were identified using a methodological framework...

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Identifiers

PMID: 33769074
DOI: 10.2217/pgs-2020-0130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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