Article
Anxa1 in smooth muscle cells protects against acute aortic dissection.
Cardiovascular research - 6 May 2022
Zhou Changping, Lin Zhiyong, Cao Huanhuan, Chen Yue, Li Jingxuan, Zhuang Xiaofeng, Ma Dong, Ji Liang, Li Wei, Xu Suowen, Pan Bing, Zheng Lemin
Abstract excerpt
AIMS: Acute aortic dissection (AAD) is a life-threatening disease with high morbidity and mortality. Previous studies have showed that vascular smooth muscle cell (VSMC) phenotype switching modulates vascular function and AAD progression. However, whether an endogenous signalling system that protects AAD progression exists remains unknown. Our aim is to investigate the role of Anxa1 in VSMC phenotype switching...
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