Article
Integrin α9 is involved in the pathopoiesis of acute aortic dissection via mediating phenotype switch of vascular smooth muscle cell.
Biochemical and biophysical research communications - 10 Dec 2020
Huang Bi, Niu Yuting, Chen Zhaoran, Yang Yanmin, Wang Xiaojian
Abstract excerpt
Acute aortic dissection (AAD) is a devastating disease with high mortality; however, the pathogenic mechanisms of AAD remain poorly understood. Our present study aimed to identify genes associated with AAD and explore the molecular function of candidate genes in the pathogenesis of AAD. We used a whole-genome transcriptional microarray to identify putative AAD genes using ascending aortic tissues from four...
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