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Article

MiR-590-3p Promotes the Phenotypic Switching of Vascular Smooth Muscle Cells by Targeting Lysyl Oxidase.

Journal of cardiovascular pharmacology - 1 Nov 2023

Wang Lei, Zhang Lin, Cui Li-Kun, Yue Xiao, Huang Li, Liu Na, Zhu Meng-Die, Wang Zheng-Bin

Abstract excerpt

ABSTRACT: We investigated the clinical characteristics of patients with acute aortic dissection (AAD) and miR-590-3p levels in serum, tissue, and vascular smooth muscle cells. The effect of miR-590-3p on the vascular smooth muscle cell phenotype was assessed, and the regulation of lysyl oxidase by miR-5903p was determined. C57BL/6 mice were used to investigate the incidence of AAD and effects of miR-5903p on AAD....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37678299
DOI: 10.1097/FJC.0000000000001483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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