Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Idd13 congenic interval defines the number of merocytic dendritic cells, a novel trait associated with autoimmune diabetes susceptibility.

Journal of autoimmunity - 1 Jun 2013

Pelletier Adam-Nicolas, Lesage Sylvie

Abstract excerpt

When antigens derived from apoptotic cells are presented by conventional dendritic cells (cDC), T cell tolerance is induced. Surprisingly, the presentation of apoptotic cell antigens by an unconventional DC subset, termed merocytic dendritic cells (mcDC), can reverse T cell anergy. The potency of mcDC at breaking T cell tolerance has been demonstrated in the context of tumors and autoimmunity, suggesting that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Count
Share to Dendritic Cells
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to Immunophenotyping

Share to Mice, Congenic

Share to Mice, Inbred NOD

Share to Mice, Knockout

Source

Identifiers

PMID: 23623717
DOI: 10.1016/j.jaut.2013.04.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Idd13 congenic interval defines the number of merocytic dendritic cells, a novel trait associated with autoimmune diabetes susceptibility.PMID 23623717Read ↗

NOD alleles at Idd1 and Idd2 loci drive exocrine pancreatic inflammation.Semantic proximity Read ↗

Production of congenic mouse strains carrying NOD-derived diabetogenic genetic intervals: an approach for the genetic dissection of complex traits.Semantic proximity Read ↗

IL-2 production by dendritic cells promotes Foxp3(+) regulatory T-cell expansion in autoimmune-resistant NOD congenic mice.Semantic proximity Read ↗

Cutting edge: the Idd3 genetic interval determines regulatory T cell function through CD11b+CD11c- APC.Semantic proximity Read ↗

Evidence of genetic epistasis in autoimmune diabetes susceptibility revealed by mouse congenic sublines.Semantic proximity Read ↗

The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.Semantic proximity Read ↗

Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.Semantic proximity Read ↗

Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice.Semantic proximity Read ↗

Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice.Semantic proximity Read ↗

Congenic mice reveal genetic epistasis and overlapping disease loci for autoimmune diabetes and listeriosis.Semantic proximity Read ↗

Molecular genetic analysis of the Idd4 locus implicates the IFN response in type 1 diabetes susceptibility in nonobese diabetic mice.Semantic proximity Read ↗

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.