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Article

The genetic predisposition to longevity acts through behavioral phenotypes in females.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Apr 2021

Van der Auwera Sandra, Garvert Linda, Fuellen Georg, Nauck Matthias, Völzke Henry, Völker Uwe, Grabe Hans J

Abstract excerpt

The discovery of genetic factors for the predisposition of longevity is promising but their functional role and clinical relevance remain largely unclear. Based on results from a large genome-wide association study (GWAS) on human longevity (N ≈ 390,000) we identified six phenotype categories belonging to behavioral and psychiatric traits showing significant genetic correlations using LD Hub. We validated these...

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Identifiers

PMID: 33730682
DOI: 10.1016/j.euroneuro.2021.02.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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