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Article

Psychosocial moderators of polygenic risk scores of inflammatory biomarkers in relation to GrimAge.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2024

Tamman Amanda J F, Koller Dora, Nagamatsu Sheila, Cabrera-Mendoza Brenda, Abdallah Chadi, Krystal John H, Gelernter Joel, Montalvo-Ortiz Janitza L, Polimanti Renato, Pietrzak Robert H

Abstract excerpt

GrimAge acceleration has previously predicted age-related morbidities and mortality. In the current study, we sought to examine how GrimAge is associated with genetic predisposition for systemic inflammation and whether psychosocial factors moderate this association. Military veterans from the National Health and Resilience in Veterans study, which surveyed a nationally representative sample of European American...

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Identifiers

PMID: 37848731
DOI: 10.1038/s41386-023-01747-5
PMCID: PMC10876568

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