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Article

E2F1 copy number variations in germline and breast cancer: a retrospective study of 222 Italian women.

Molecular medicine (Cambridge, Mass.) - 10 Mar 2021

Rocca Maria Santa, Benna Clara, Goldin Elena, Di Nisio Andrea, De Toni Luca, Cosci Ilaria, Marchet Alberto, Nitti Donato, Foresta Carlo

Abstract excerpt

BACKGROUND: Breast cancer is the most common neoplasia among women in developed countries. The risk factors of breast cancer can be distinguished in modifiable and unmodifiable factors and, among the latter, genetic factors play a key role. Copy number variations (CNVs) are genetic variants that are classified as rare when present in less than 1% of the healthy population. Since rare CNVs are often cause of...

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Identifiers

PMID: 33691613
DOI: 10.1186/s10020-021-00287-2
PMCID: PMC7948349

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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