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Article

Germline copy number variants are not associated with globally acquired copy number changes in familial breast tumours.

Breast cancer research and treatment - 1 Aug 2012

Walker Logan C, Krause Lutz, Spurdle Amanda B, Waddell Nic

Abstract excerpt

A characteristic of sporadic and familial breast tumours is genomic instability, resulting from either inherited mutations in genes that control genome integrity or mutations that are acquired in somatic cells during development. It is well established that abnormal chromosome number and structural changes to chromosomes play an important role in the cause and progression of breast cancer. Familial BRCA1 breast...

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Identifiers

PMID: 22434526
DOI: 10.1007/s10549-012-2024-6
PMCID: PMC3409366

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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