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Article

Germline copy number variations are associated with breast cancer risk and prognosis.

Scientific reports - 7 Nov 2017

Kumaran Mahalakshmi, Cass Carol E, Graham Kathryn, Mackey John R, Hubaux Roland, Lam Wan, Yasui Yutaka, Damaraju Sambasivarao

Abstract excerpt

Breast cancer is one of the most common cancers among women, and susceptibility is explained by genetic, lifestyle and environmental components. Copy Number Variants (CNVs) are structural DNA variations that contribute to diverse phenotypes via gene-dosage effects or cis-regulation. In this study, we aimed to identify germline CNVs associated with breast cancer susceptibility and their relevance to prognosis. We...

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Identifiers

PMID: 29116104
DOI: 10.1038/s41598-017-14799-7
PMCID: PMC5677082

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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