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Article

Copy number alterations and copy number variation in cancer: close encounters of the bad kind.

Cytogenetic and genome research - 1 Jan 2008

Speleman F, Kumps C, Buysse K, Poppe B, Menten B, De Preter K

Abstract excerpt

Recent studies have unveiled copy number variants (CNVs) as an important source of genetic variation. Many of these CNVs contain coding sequences, which have been shown to be dosage sensitive. Evidence is accumulating that certain CNVs have impact on susceptibility to human diseases such as HIV infection and autoimmune diseases, as well as on adaptability to environmental conditions or nutrition. The possible...

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PMID: 19287153
DOI: 10.1159/000184706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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