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Article

Increased genomic burden of germline copy number variants is associated with early onset breast cancer: Australian breast cancer family registry.

Breast cancer research : BCR - 16 Mar 2017

Walker Logan C, Pearson John F, Wiggins George A R, Giles Graham G, Hopper John L, Southey Melissa C

Abstract excerpt

BACKGROUND: Women with breast cancer who have multiple affected relatives are more likely to have inherited genetic risk factors for the disease. All the currently known genetic risk factors for breast cancer account for less than half of the average familial risk. Furthermore, the genetic factor(s) underlying an increased cancer risk for many women from multiple-case families remain unknown. Rare genomic...

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Identifiers

PMID: 28302160
DOI: 10.1186/s13058-017-0825-6
PMCID: PMC5356248

Genes

BLM
BRCA1
SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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