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Article

Copy number variations of E2F1: a new genetic risk factor for testicular cancer.

Endocrine-related cancer - 1 Mar 2017

Rocca Maria Santa, Di Nisio Andrea, Marchiori Arianna, Ghezzi Marco, Opocher Giuseppe, Foresta Carlo, Ferlin Alberto

Abstract excerpt

Testicular germ cell tumor (TGCT) is one of the most heritable forms of cancer. In last years, many evidence suggested that constitutional genetic factors, mainly single nucleotide polymorphisms, can increase its risk. However, the possible contribution of copy number variations (CNVs) in TGCT susceptibility has not been substantially addressed. Indeed, an increasing number of studies have focused on the effect...

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Share to Cell Line, Tumor
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to E2F1 Transcription Factor

Share to Neoplasms, Germ Cell and Embryonal

Share to Proto-Oncogene Proteins c-akt

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Share to Testicular Neoplasms

Share to TOR Serine-Threonine Kinases

Source

Identifiers

PMID: 28104681
DOI: 10.1530/ERC-16-0514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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