Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Smooth Muscle Cell-Specific PKM2 (Pyruvate Kinase Muscle 2) Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia.

Arteriosclerosis, thrombosis, and vascular biology - 5 May 2021

Jain Manish, Dhanesha Nirav, Doddapattar Prakash, Nayak Manasa K, Guo Liang, Cornelissen Anne, Lentz Steven R, Finn Aloke V, Chauhan Anil K

Abstract excerpt

[Figure: see text].

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Artery Injuries
Share to Glycolysis
Share to Hyperplasia

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Neointima

Share to Pyruvate Kinase

Share to Thyroid Hormones

Source

Open in PubMed Open full text

Identifiers

PMID: 33691477
DOI: 10.1161/ATVBAHA.121.316021
PMCID: PMC8062279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Smooth Muscle Cell-Specific PKM2 (Pyruvate Kinase Muscle 2) Promotes Smooth Muscle Cell Phenotypic Switching and Neointimal Hyperplasia.PMID 33691477Read ↗

Targeting PDK4 attenuates neointimal hyperplasia and regulates VSMC phenotypic switching, apoptosis, and autophagy.Semantic proximity Read ↗

An update on the phenotypic switching of vascular smooth muscle cells in the pathogenesis of atherosclerosis.Semantic proximity Read ↗

PHB2 Maintains the Contractile Phenotype of VSMCs by Counteracting PKM2 Splicing.Semantic proximity Read ↗

Regulation of Ptbp1-controlled alternative splicing of pyruvate kinase muscle by liver kinase B1 governs vascular smooth muscle cell plasticity in vivo.Semantic proximity Read ↗

Role of Krüppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells.Semantic proximity Read ↗

Molecular and cellular phenotypes and their regulation in smooth muscle.Semantic proximity Read ↗

KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells.Semantic proximity Read ↗

RIMKLA promotes hypertension by activating PKM2 to trigger VSMC phenotype switch.Semantic proximity Read ↗

Metabolic control of smooth muscle cell phenotype switching in atherosclerosisSemantic proximity Read ↗

Glycolysis and de novo fatty acid synthesis cooperatively regulate pathological vascular smooth muscle cell phenotypic switching and neointimal hyperplasia.Semantic proximity Read ↗

Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch.Semantic proximity Read ↗

Protein kinase C isoform expression and ATP response change with smooth muscle cell differentiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.