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Article

The M domain in UNC-13 regulates the probability of neurotransmitter release.

Cell reports - 9 Mar 2021

Liu Haowen, Li Lei, Sheoran Seema, Yu Yi, Richmond Janet E, Xia Jingyao, Tang Jing, Liu Jie, Hu Zhitao

Abstract excerpt

Synapses exhibit multiple forms of short-term plasticities, which have been attributed to the heterogeneity of neurotransmitter release probability. However, the molecular mechanisms that underlie the differential release states remain to be fully elucidated. The Unc-13 proteins appear to have key roles in synaptic function through multiple regulatory domains. Here, we report that deleting the M domain in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33691106
DOI: 10.1016/j.celrep.2021.108828
PMCID: PMC8066380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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