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Article

Shared associations identify causal relationships between gene expression and immune cell phenotypes.

Communications biology - 4 Mar 2021

Gasperi Christiane, Chun Sung, Sunyaev Shamil R, Cotsapas Chris

Abstract excerpt

Genetic mapping studies have identified thousands of associations between common variants and hundreds of human traits. Translating these associations into mechanisms is complicated by two factors: they fall into gene regulatory regions; and they are rarely mapped to one causal variant. One way around these limitations is to find groups of traits that share associations, using this genetic link to infer a...

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Share to Gene Expression Regulation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33664438
DOI: 10.1038/s42003-021-01823-w
PMCID: PMC7933159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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