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Article

Genetic insights into common pathways and complex relationships among immune-mediated diseases.

Nature reviews. Genetics - 1 Sept 2013

Parkes Miles, Cortes Adrian, van Heel David A, Brown Matthew A

Abstract excerpt

Shared aetiopathogenic factors among immune-mediated diseases have long been suggested by their co-familiality and co-occurrence, and molecular support has been provided by analysis of human leukocyte antigen (HLA) haplotypes and genome-wide association studies. The interrelationships can now be better appreciated following the genotyping of large immune disease sample sets on a shared SNP array: the...

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Alleles
Chromosome Mapping
Environment
Gene-Environment Interaction
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immune System Diseases

Quantitative Trait Loci

Signal Transduction

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PMID: 23917628
DOI: 10.1038/nrg3502

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