Article
The uptake rate of risk-reducing salpingo-oophorectomy among Thai women with breast cancer and germline BRCA pathogenic or likely pathogenic variants.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2026
Pradutchon Supapan, Pithukpakorn Manop, Poonyakanok Vitcha
Abstract excerpt
Germline BRCA1 and BRCA2 pathogenic and likely pathogenic variants (PVs) significantly increase the risk of breast cancer and ovarian cancer, forming the basis for hereditary breast and ovarian cancer syndrome. Current guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with PVs. This study aimed to evaluate the rate of uptake of RRSO among women with breast cancer who carry germline BRCA...
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