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Article

Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization.

Molecular pain - 1 Jan 2000

Zhou Feng, Wang Xian, Han Baoyu, Tang Xiaohui, Liu Ru, Ji Qing, Zhou Zhiqiang, Zhang Lidong

Abstract excerpt

Microglia activation and subsequent pro-inflammatory responses play a key role in the development of neuropathic pain. The process of microglia polarization towards pro-inflammatory phenotype often occurs during neuroinflammation. Recent studies have demonstrated an active role for the gut microbiota in promoting microglial full maturation and inflammatory capabilities via the production of Short-Chain Fatty...

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Identifiers

PMID: 33626986
DOI: 10.1177/1744806921996520
PMCID: PMC7925956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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