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Article

Research Progress on Treating Spinal Cord Injury by Modulating the Phenotype of Microglia.

Journal of integrative neuroscience - 19 Sept 2024

Yu Qinghe, Cai Ziming, Liu Xiaofeng, Lin Shuhui, Li Pian, Ruan Ye, Liang Jinzhu, He Xu, Lin Wenping

Abstract excerpt

Spinal cord injury (SCI) is a severe central nervous system disorder with no currently available effective treatment. Microglia are immune cells in the central nervous system that play crucial roles in the SCI occurrence, development, and recovery stages. They exhibit dynamic polarization over time and can switch between classical activation (M1) and alternative activation (M2) phenotypes to respond to...

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PMID: 39344231
DOI: 10.31083/j.jin2309171

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