Article
PICS2: next-generation fine mapping via probabilistic identification of causal SNPs.
Bioinformatics (Oxford, England) - 29 Sept 2021
Taylor Kimberly E, Ansel K Mark, Marson Alexander, Criswell Lindsey A, Farh Kyle Kai-How
Abstract excerpt
SUMMARY: The Probabilistic Identification of Causal SNPs (PICS) algorithm and web application was developed as a fine-mapping tool to determine the likelihood that each single nucleotide polymorphism (SNP) in LD with a reported index SNP is a true causal polymorphism. PICS is notable for its ability to identify candidate causal SNPs within a locus using only the index SNP, which are widely available from...
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