Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation and expression alterations of histone methylation-related NSD2, KDM2B and SETMAR genes in colon cancers.

Pathology, research and practice - 1 Mar 2021

Moon Seong Won, Son Hyun Ji, Mo Ha Yoon, Choi Eun Ji, Yoo Nam Jin, Lee Sug Hyung

Abstract excerpt

Epigenetic dysregulation is a hallmark of cancers, and examples of its cancer-associated expression and mutation alterations are rapidly growing. Histone methylation, a process by which methyl groups are transferred to amino acids of histone proteins, is crucial for the epigenetic gene regulation. NSD2 (nuclear receptor-binding SET domain protein 2) and SETMAR are epigenetic regulators for histone methylation....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogenesis
Share to Colonic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to F-Box Proteins

Share to Histone-Lysine N-Methyltransferase

Share to Jumonji Domain-Containing Histone Demethylases

Share to Microsatellite Instability

Share to Stomach Neoplasms

Source

Identifiers

PMID: 33621919
DOI: 10.1016/j.prp.2021.153354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation and expression alterations of histone methylation-related NSD2, KDM2B and SETMAR genes in colon cancers.PMID 33621919Read ↗

Clinical and histopathologic characterization of SETD2-mutated colorectal cancer.Semantic proximity Read ↗

Regional bias of tumor suppressor gene mutations of STARD8 and WNK2 in colon cancers.Semantic proximity Read ↗

Pan-cancer analysis of SETD2 mutation and its association with the efficacy of immunotherapySemantic proximity Read ↗

Analysis of the role of mutations in the KMT 2D histone lysine methyltransferase in bladder cancerSemantic proximity Read ↗

SETD2: an epigenetic modifier with tumor suppressor functionality.Semantic proximity Read ↗

Expression Profile, Prognostic Value, and Therapeutic Potential of NSD2 in Pan-Cancer: A Systematic Analysis Integrating Multi-Omics DataSemantic proximity Read ↗

Distinct Molecular and Prognostic Profiles of Left- and Right-Sided Colorectal Cancer Revealed by NGS Analysis: The Role of SMAD4 and SETD2 Mutations.Semantic proximity Read ↗

The NSD family of protein methyltransferases in human cancer.Semantic proximity Read ↗

The Role of Nuclear Receptor-Binding SET Domain Family Histone Lysine Methyltransferases in Cancer.Semantic proximity Read ↗

SETD2 variation correlates with tumor mutational burden and MSI along with improved response to immunotherapy.Semantic proximity Read ↗

SETD2 as a regulator of N6-methyladenosine RNA methylation and modifiers in cancer.Semantic proximity Read ↗

Deficiency of histone H3K36 methyltransferase SETD2 inhibits proliferation and migration of hepatocellular carcinoma through ERK pathwaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.