Article
Regional bias of tumor suppressor gene mutations of STARD8 and WNK2 in colon cancers.
Pathology, research and practice - 1 Jan 2024
Mo Ha Yoon, Moon Seong Won, An Chang Hyeok, Lee Sug Hyung
Abstract excerpt
StAR-related lipid transfer domain protein 8 (STARD8), encoding a Rho-GTPase-activating protein, and WNK2, encoding a serine/threonine kinase are candidate tumor suppressor genes (TSGs) in human cancers. Inactivation of these genes that would promote cancer pathogenesis is largely unknown in colon cancer (CC). Our study addressed to address whether STARD8 and WNK2 genes are mutated in CC. STARD8 and WNK2 genes...
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