Article

Expression Profile, Prognostic Value, and Therapeutic Potential of NSD2 in Pan-Cancer: A Systematic Analysis Integrating Multi-Omics Data

2026-08-04

Abstract excerpt

<title>Abstract</title> <p>This study systematically profiles NSD2, a key histone methyltransferase, across 33 distinct cancer types using comprehensive integrated multi-omics data. NSD2 exhibits synchronous mRNA and protein overexpression in multiple common tumors, with its expression levels progressively rising alongside advancing clinical stages and pathological grades. It achieves a diagnostic AUC ≥ 0.7 in 17...

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Literature Corpus work: 966ce67f-278d-5347-a519-6655686e5227
DOI: 10.21203/rs.3.rs-10347526/v1

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