Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.

Communications biology - 18 Feb 2021

Huang Ya-Lang, Huang Ming-Ting, Sung Pei-Shan, Chou Teh-Ying, Yang Ruey-Bing, Yang An-Suei, Yu Chung-Ming, Hsu Yu-Wen, Chang Wei-Chiao, Hsieh Shie-Liang

Abstract excerpt

Human C-type lectin member 18A (CLEC18A) is ubiquitously expressed in human, and highest expression levels are found in human myeloid cells and liver. In contrast, mouse CLEC18A (mCLEC18A) is only expressed in brain, kidney and heart. However, the biological functions of CLEC18A are still unclear. We have shown that a single amino acid change (S339 →R339) in CTLD domain has profound effect in their binding to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endosomes
Share to Inflammation Mediators

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H5N1 Subtype

Share to Lectins, C-Type

Share to Madin Darby Canine Kidney Cells

Share to Orthomyxoviridae Infections

Share to Poly I-C

Share to Toll-Like Receptor 3

Source

Open in PubMed Open full text

Identifiers

PMID: 33603190
DOI: 10.1038/s42003-021-01745-7
PMCID: PMC7893028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endosomal TLR3 co-receptor CLEC18A enhances host immune response to viral infection.PMID 33603190Read ↗

CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In VivoSemantic proximity Read ↗

CD1d-mediated activation of group 3 innate lymphoid cells drives IL-22 production.Semantic proximity Read ↗

The C-type lectin receptor CLECSF8/CLEC4D is a key component of anti-mycobacterial immunity.Semantic proximity Read ↗

The Superior Ability of Human BDCA3+ (CD141+) Dendritic Cells (DCs) to Cross-Present Antigens Derived From Necrotic Lung Cancer CellsSemantic proximity Read ↗

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.Semantic proximity Read ↗

Characterization of the genetic variation and evolutionary divergence of the CLEC18 family.Semantic proximity Read ↗

UNC93B1 mediates differential trafficking of endosomal TLRs.Semantic proximity Read ↗

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis.Semantic proximity Read ↗

TRIM29 controls enteric RNA virus-induced intestinal inflammation by targeting NLRP6 and NLRP9b signaling pathwaysSemantic proximity Read ↗

KLRE1 shapes antifungal immunity by tuning dendritic cell and T cell activation through distinct heterodimeric partnersSemantic proximity Read ↗

Langerin functions as an antiviral receptor on Langerhans cellsSemantic proximity Read ↗

Role of A20 in interferon-α-mediated functional restoration of myeloid dendritic cells in patients with chronic hepatitis C.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.