Article
CD1d-mediated activation of group 3 innate lymphoid cells drives IL-22 production.
EMBO reports - 1 Jan 2017
Saez de Guinoa Julia, Jimeno Rebeca, Farhadi Nazanin, Jervis Peter J, Cox Liam R, Besra Gurdyal S, Barral Patricia
Abstract excerpt
Innate lymphoid cells (ILCs) are a heterogeneous family of immune cells that play a critical role in a variety of immune processes including host defence against infection, wound healing and tissue repair. Whether these cells are involved in lipid-dependent immunity remains unexplored. Here we show that murine ILCs from a variety of tissues express the lipid-presenting molecule CD1d, with group 3 ILCs (ILC3s)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
