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Article

Characterization of the genetic variation and evolutionary divergence of the CLEC18 family.

Journal of biomedical science - 20 May 2024

Chang Che-Mai, Chang Wei-Chiao, Hsieh Shie-Liang

Abstract excerpt

BACKGROUND: The C-type lectin family 18 (CLEC18) with lipid and glycan binding capabilities is important to metabolic regulation and innate immune responses against viral infection. However, human CLEC18 comprises three paralogous genes with highly similar sequences, making it challenging to distinguish genetic variations, expression patterns, and biological functions of individual CLEC18 paralogs. Additionally,...

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Identifiers

PMID: 38764023
DOI: 10.1186/s12929-024-01034-5
PMCID: PMC11103991

Genes

CLEC18A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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