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Article

Assessment of a Split Homing Based Gene Drive for Efficient Knockout of Multiple Genes.

G3 (Bethesda, Md.) - 6 Feb 2020

Kandul Nikolay P, Liu Junru, Buchman Anna, Gantz Valentino M, Bier Ethan, Akbari Omar S

Abstract excerpt

Homing based gene drives (HGD) possess the potential to spread linked cargo genes into natural populations and are poised to revolutionize population control of animals. Given that host encoded genes have been identified that are important for pathogen transmission, targeting these genes using guide RNAs as cargo genes linked to drives may provide a robust method to prevent disease transmission. However,...

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Identifiers

PMID: 31882406
DOI: 10.1534/g3.119.400985
PMCID: PMC7003086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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