Article
The Role of Tbx20 in Cardiovascular Development and Function
28 Jan 2021
Abstract excerpt
Tbx20is a member of the Tbx1 subfamily of T-box-containing genes and is known to play a variety of fundamental roles in cardiovascular development and homeostasis as well as cardiac remodeling in response to pathophysiological stresses. Mutations inTBX20are widely associated with the complex spectrum of congenital heart defects (CHDs) in humans, which includes defects in chamber septation, chamber growth, and...
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