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Article

The BMP pathway acts to directly regulate <i>Tbx20</i> in the developing heart

11 May 2010

Abstract excerpt

TBX20 has been shown to be essential for vertebrate heart development. Mutations within the TBX20 coding region are associated with human congenital heart disease, and the loss of Tbx20 in a wide variety of model systems leads to cardiac defects and eventually heart failure. Despite the crucial role of TBX20 in a range of cardiac cellular processes, the signal transduction pathways that act upstream of Tbx20...

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PMID: 20460370
DOI: 10.1242/dev.043588

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The BMP pathway acts to directly regulate <i>Tbx20</i> in the developing heartPMID 20460370Read ↗

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