Article
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.
Developmental biology - 15 Oct 2003
Stennard Fiona A, Costa Mauro W, Elliott David A, Rankin Scott, Haast Saskia J P, Lai Donna, McDonald Lachlan P A, Niederreither Karen, Dolle Pascal, Bruneau Benoit G, Zorn Aaron M, Harvey Richard P
Abstract excerpt
Tbx20 is a member of the T-box transcription factor family expressed in the forming hearts of vertebrate and invertebrate embryos. We report here analysis of Tbx20 expression during murine cardiac development and assessment of DNA-binding and transcriptional properties of Tbx20 isoforms. Tbx20 was expressed in myocardium and endocardium, including high levels in endocardial cushions. cDNAs generated by...
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