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Article

Behavioural Characterisation of Macrod1 and Macrod2 Knockout Mice.

Cells - 10 Feb 2021

Crawford Kerryanne, Oliver Peter L, Agnew Thomas, Hunn Benjamin H M, Ahel Ivan

Abstract excerpt

Adenosine diphosphate ribosylation (ADP-ribosylation; ADPr), the addition of ADP-ribose moieties onto proteins and nucleic acids, is a highly conserved modification involved in a wide range of cellular functions, from viral defence, DNA damage response (DDR), metabolism, carcinogenesis and neurobiology. Here we study MACROD1 and MACROD2 (mono-ADP-ribosylhydrolases 1 and 2), two of the least well-understood...

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Identifiers

PMID: 33578760
DOI: 10.3390/cells10020368
PMCID: PMC7916507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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