Article
Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin.
Molecular and cellular biology - 1 Dec 2010
Changolkar Lakshmi N, Singh Geetika, Cui Kairong, Berletch Joel B, Zhao Keji, Disteche Christine M, Pehrson John R
Abstract excerpt
Studies of macroH2A histone variants indicate that they have a role in regulating gene expression. To identify direct targets of the macroH2A1 variants, we produced a genome-wide map of the distribution of macroH2A1 nucleosomes in mouse liver chromatin using high-throughput DNA sequencing. Although macroH2A1 nucleosomes are widely distributed across the genome, their local concentration varies over a range of...
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