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Tissue Thiol Concentration in High-Grade Gliomas: Is There any Association Between IDH1 Mutation Presence and Tumoral Cellular Antioxidant Defense?

Turkish neurosurgery - 1 Jan 2021

Evran Sevket, Kayhan Ahmet, Baran Oguz, Cevik Serdar, Katar Salim, Kaya Mustafa, Sonmez Derya, Serin Huriye, Hanimoglu Hakan, Kaynar Mehmet Yasar

Abstract excerpt

AIM: To assess and compare the antioxidant capacities of high-grade gliomas (HGG) according to their grades and the presence of isocitrate dehydrogenase 1 (IDH1) mutation using tissue thiol level measurement. MATERIAL AND METHODS: Tissue thiol concentrations were measured in 41 HGG samples and 21 healthy brain tissues obtained from autopsy procedures, which were performed within the first 4 hours of death. All...

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PMID: 33575999
DOI: 10.5137/1019-5149.JTN.31866-20.2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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