Article

Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production

2021-09-11

Abstract excerpt

<h4>Summary</h4> Glucose and amino acid metabolism are critical for glioblastoma (GBM) growth, but little is known about the specific metabolic alterations in GBM that are targetable with FDA-approved compounds. To investigate tumor metabolism signatures unique to GBM, we interrogated The Cancer Genome Atlas for alterations in glucose and amino acid signatures in GBM relative to other human cancers and found that...

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Literature Corpus work: f4d0688e-458d-5479-8608-7ff3fddb3f19
DOI: 10.1101/2021.09.10.459864

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