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Article

Distinguishing IDH mutation status in gliomas using FTIR-ATR spectra of peripheral blood plasma indicating clear traces of protein amyloid aggregation.

BMC cancer - 16 Feb 2024

Kino Saiko, Kanamori Masayuki, Shimoda Yoshiteru, Niizuma Kuniyasu, Endo Hidenori, Matsuura Yuji

Abstract excerpt

BACKGROUND: Glioma is a primary brain tumor and the assessment of its molecular profile in a minimally invasive manner is important in determining treatment strategies. Among the molecular abnormalities of gliomas, mutations in the isocitrate dehydrogenase (IDH) gene are strong predictors of treatment sensitivity and prognosis. In this study, we attempted to non-invasively diagnose glioma development and the...

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Source

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Identifiers

PMID: 38365669
DOI: 10.1186/s12885-024-11970-y
PMCID: PMC10870484

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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