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Article

Post-Transcriptional Regulation of PARP7 Protein Stability Is Controlled by Androgen Signaling

9 Feb 2021

Abstract excerpt

Poly-ADP-ribose polymerases (PARPs) are enzymes that catalyze ADP-ribosylation and play critical roles in normal and disease settings. The PARP family member, PARP7, is a mono-ADP-ribosyltransferase that has been suggested to play a tumor suppressive role in breast, ovarian, and colorectal cancer. Here, we have investigated how androgen signaling regulates PARP7 homeostasis in prostate cancer cells, where PARP7...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33572475
DOI: 10.3390/cells10020363

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