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Article

Performance Characteristics of Mutational Signature Analysis in Targeted Panel Sequencing.

Archives of pathology & laboratory medicine - 1 Nov 2021

Lawrence Lauren, Kunder Christian A, Fung Eula, Stehr Henning, Zehnder James

Abstract excerpt

CONTEXT.—: Mutational signatures have been described in the literature and a few centers have implemented pipelines for clinical reporting. OBJECTIVE.—: To describe the performance of a mutational signature caller with clinical samples sequenced on a targeted next-generation sequencing panel with a small genomic footprint. DESIGN.—: One thousand six hundred eighty-two clinical samples were analyzed for the...

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Identifiers

PMID: 33571361
DOI: 10.5858/arpa.2020-0536-OA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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