Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the Discovery, Prediction, and Exploration of Mutational Signatures.

Cancer research - 1 Dec 2021

Chevalier Aaron, Yang Shiyi, Khurshid Zainab, Sahelijo Nathan, Tong Tong, Huggins Jonathan H, Yajima Masanao, Campbell Joshua D

Abstract excerpt

Mutational signatures are patterns of somatic alterations in the genome caused by carcinogenic exposures or aberrant cellular processes. To provide a comprehensive workflow for preprocessing, analysis, and visualization of mutational signatures, we created the Mutational Signature Comprehensive Analysis Toolkit (musicatk) package. musicatk enables users to select different schemas for counting mutation types and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Databases, Factual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Gene Expression Regulation, Neoplastic

Share to Mutation

Share to Neoplasms

Share to Prognosis

Share to Workflow

Source

Open in PubMed Open full text

Identifiers

PMID: 34625425
DOI: 10.1158/0008-5472.CAN-21-0899
PMCID: PMC8639789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the Discovery, Prediction, and Exploration of Mutational Signatures.PMID 34625425Read ↗

The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the discovery, prediction, and exploration of mutational signaturesSemantic proximity Read ↗

Analysis of mutational signatures with yet another package for signature analysis.Semantic proximity Read ↗

Mutational signatures: experimental design and analytical frameworkSemantic proximity Read ↗

Learning mutational signatures and their multidimensional genomic properties with TensorSignaturesSemantic proximity Read ↗

Portrait of a cancer: mutational signature analyses for cancer diagnosticsSemantic proximity Read ↗

Clinical and genomic characterization of mutational signatures across human cancers.Semantic proximity Read ↗

Huge Genome Study Uncovers Mutational Signatures.Semantic proximity Read ↗

A real-world pan-cancer catalogue of mutational signatures from 111,711 tumorsSemantic proximity Read ↗

mSignatureDB: a database for deciphering mutational signatures in human cancers.Semantic proximity Read ↗

CANCERSIGN: a user-friendly and robust tool for identification and classification of mutational signatures and patterns in cancer genomesSemantic proximity Read ↗

MutSpec: a Galaxy toolbox for streamlined analyses of somatic mutation spectra in human and mouse cancer genomes.Semantic proximity Read ↗

The repertoire of mutational signatures in human cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.