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Article

Investigation on the Role of PALB2 Gene in CDH1-Negative Patients With Hereditary Diffuse Gastric Cancer.

Clinical and translational gastroenterology - 1 Dec 2020

Carreño Marta, Pena-Couso Laura, Mercadillo Fátima, Perea José, Urioste Miguel

Abstract excerpt

INTRODUCTION: Not all patients with hereditary diffuse gastric cancer (HDGC) are found to carry germline pathogenic variants in the associated gene CDH1, which translates into a challenging clinical management and poor cancer prevention. Thus, several studies have searched for other candidate genes, among which stands PALB2. Our work explores the implication of this known cancer gene in HDGC. METHODS: We searched...

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Identifiers

PMID: 33512806
DOI: 10.14309/ctg.0000000000000280
PMCID: PMC7721210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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