Article
Clinical Implication of CDH1 Mutations in Genetic Testing for Diffuse Gastric Cancer Patients.
Oncology - 1 Jan 2024
Corso Giovanni, Trovato Cristina Maria, Petitto Salvatore, Girardi Antonia, De Scalzi Alessandra Margherita, Bianchi Beatrice, Magnoni Francesca, Cioffi Antonio, Galimberti Viviana, Veronesi Paolo, Mazzarol Giovanni, Maisonneuve Patrick
Abstract excerpt
INTRODUCTION: The objective of this study was to reclassify published germline CDH1 variants identified in gastric cancer (GC) in accordance with the latest ClinVar definition and to correlate their pathogenicity with the established international clinical criteria for genetic testing. METHODS: T...
Topics
- Humans
- Genetic Predisposition to Disease
- Stomach Neoplasms
- Pedigree
- Genetic Testing
- Germ-Line Mutation
- Cadherins
- Adenocarcinoma
- Antigens, CD