Associations between Inflammatory Cytokine Gene Polymorphisms and Susceptibilities to Intracranial Aneurysm in Chinese Population.

doi:10.1155/2021/8865601

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Article

Associations between Inflammatory Cytokine Gene Polymorphisms and Susceptibilities to Intracranial Aneurysm in Chinese Population.

BioMed research international - 1 Jan 2021

Xu Lu, Hu Liming, Hu Chongyu, Liu Junyu, Li Bingyang, Liao Xin, Zhou Jilin, Liu Songlin, Li Yifeng, Yuan Dun, Jiang Weixi, Yan Junxia

Abstract excerpt

Intracranial aneurysm (IA) is a complex disease caused by genetic and environmental factors. Evidence indicates that inflammation plays an important role in IA occurrence. We aimed to explore the associations between inflammatory cytokine gene polymorphisms and IA in a Chinese population. This study enrolled 768 participants of Han ethnicity, including 384 patients with IA and 384 healthy individuals. Sixteen...

Topics

Aged
Asian People
Case-Control Studies
Cytokines
Female
Genetic Predisposition to Disease
Humans
Inflammation
Interleukin-12 Subunit p40
Interleukin-1alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interleukin-6

Intracranial Aneurysm

Linkage Disequilibrium

Male

Middle Aged

Polymorphism, Single Nucleotide

Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 33511216
DOI: 10.1155/2021/8865601
PMCID: PMC7826207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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