Association of TNF-α-3959T/C Gene Polymorphisms in the Chinese Population with Intracranial Aneurysms.

doi:10.1007/s12031-017-0985-y

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Article

Association of TNF-α-3959T/C Gene Polymorphisms in the Chinese Population with Intracranial Aneurysms.

Journal of molecular neuroscience : MN - 1 Dec 2017

Hu Juntao, Luo Jie, Wang Hui, Wang Chaojia, Sun Xiaodong, Li Anrong, Zhou Yi, Liu Yuhang, Chen Qianxue

Abstract excerpt

Recent studies have demonstrated that cytokines play an important role in the pathogenesis of intracranial aneurysm (IA). Tumor necrosis factor-α (TNF-α) is an important proinflammatory cytokine, which was shown to influence the development of IA, but there is no research data from China. Hence, the purpose of this study was to explore the relationship between TNF-α polymorphisms and IA in China. The association...

Topics

Adolescent
Adult
Aged
Case-Control Studies
China
Female
Humans
Intracranial Aneurysm
Male
Middle Aged
Polymorphism, Single Nucleotide
Tumor Necrosis Factor-alpha

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Open in PubMed

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PMID: 29027627
DOI: 10.1007/s12031-017-0985-y

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