Article
Pathogenesis of intracranial aneurysm is mediated by proinflammatory cytokine TNFA and IFNG and through stochastic regulation of IL10 and TGFB1 by comorbid factors.
Journal of neuroinflammation - 22 Jul 2015
Sathyan Sanish, Koshy Linda V, Srinivas Lekshmy, Srinivas Lekshmi, Easwer H V, Premkumar S, Nair Suresh, Bhattacharya R N, Alapatt Jacob P, Banerjee Moinak
Abstract excerpt
BACKGROUND: Intracranial aneurysm (IA) is often asymptomatic until the time of rupture resulting in subarachnoid hemorrhage (SAH).There is no precise biochemical or phenotype marker for diagnosis of aneurysm. Environmental risk factors that associate with IA can result in modifying the effect of inherited genetic factors and thereby increase the susceptibility to SAH. In addition subsequent to aneurismal rupture,...
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